Expresión de búsqueda: RNA, SMALL INTERFERING 
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Descriptor Inglés:   RNA, Small Interfering 
Descriptor Español:   ARN Interferente Pequeño 
Descriptor Portugués:   RNA Interferente Pequeno 
Sinónimos Inglés:   Short Hairpin RNA
Short Interfering RNA
Small Hairpin RNA
Small Interfering RNA
piRNA
scnRNA
shRNA
tasiRNA
Hairpin RNA, Short
Hairpin RNA, Small
Interfering RNA, Short
Interfering RNA, Small
Piwi Interacting RNA
RNA, Piwi Interacting
RNA, Short Hairpin
RNA, Short Interfering
RNA, Small Hairpin
RNA, Small Scan
Repeat Associated siRNA
Scan RNA, Small
Trans Acting siRNA
siRNA, Repeat Associated
siRNA, Trans Acting
Piwi-Interacting RNA
Repeat-Associated siRNA
RNA, Piwi-Interacting
RNA, Scan
Scan RNA
siRNA
siRNA, Repeat-Associated
siRNA, Trans-Acting
Small Scan RNA
Trans-Acting siRNA  
Categoría:   D13.150.650.700
D13.444.735.150.700
D13.444.735.790.552.875
Definición Inglés:   Small double-stranded, non-protein coding RNAs (21-31 nucleotides) involved in GENE SILENCING functions, especially RNA INTERFERENCE (RNAi). Endogenously, siRNAs are generated from dsRNAs (RNA, DOUBLE-STRANDED) by the same ribonuclease, Dicer, that generates miRNAs (MICRORNAS). The perfect match of the siRNAs' antisense strand to their target RNAs mediates RNAi by siRNA-guided RNA cleavage. siRNAs fall into different classes including trans-acting siRNA (tasiRNA), repeat-associated RNA (rasiRNA), small-scan RNA (scnRNA), and Piwi protein-interacting RNA (piRNA) and have different specific gene silencing functions. 
Nota de Indización Inglés:   Do not confuse with defective interfering RNA (diRNA), a viral RNA of DEFECTIVE VIRUSES.
Relacionados Inglés:   MicroRNAs
RNA Interference
RNA-Induced Silencing Complex
 
Nota Histórica Inglés:   2003; use RNA, SMALL INTERFERING (NM) 2001-2002 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   37536 
Identificador Único:   D034741 

Ocurrencia en la BVS:
 

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